Well, you first need to convince journal editors that the manuscript meets the standards of their journal.
Editors go through a large number of manuscripts monthly; for journals such as Science, each editor can go through hundreds! So you need to make a good first impression, since you probably have only a few minutes of the editor’s time. A few minutes where the manuscript is accepted for detailed evaluation and peer review, or rejected outright!
How do you convince the editor? What goes into the manuscript and supporting material?
You might as well ask the editor!
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